
Eastern Panama Vacations from $603
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Your Eastern Panama Vacation
Leave all the planning to us with an Eastern Panama vacation package. With everything organized before you jet off, all you need to do is sit back, chill out and experience this destination's many wonders. Where to start your journey? In the most popular cities, of course. Isla Tigre and Palenque are two great places to kick off your itinerary during your trip to Eastern Panama. When it's time to stop daydreaming and start doing, Expedia will help turn your Eastern Panama vacation into reality.
The Latest Eastern Panama vacation packages

Villa Botero By Casa Mojito B&B
Reviewed on Apr 18, 2025

Hotel Posada Los Delfines
Reviewed on Mar 19, 2025



Discover the most popular places to visit in Eastern Panama
Cayos Holandeses
Commune with nature and explore the great outdoors at Cayos Holandeses during your travels in San Blas Islands. Stroll along the seaside or experience the area's festivals.
Museum of the Kuna Nation
You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Masargantupo. Stroll along the seaside or experience the area's festivals.
Porvenir Museum
You can spend time browsing the exhibits at Porvenir Museum during your travels in Narganá. Amble around the area's seaside or experience its festivals.
Eastern Panama Hotel Deals

Reviewed on Feb 16, 2022

Reviewed on Apr 19, 2025

Find the Best Eastern Panama Vacation Packages
Eastern Panama Essential Information
Language | Spanish |
---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Tocumen Intl. Airport (PTY) |